Morgan Levine, PhD
Assistant Professor of Pathology and Epidemiology at Yale School of Medicine, USA Dr. Levine is an Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of both the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging. Her work relies on an interdisciplinary approach, integrating theories and methods from statistical genetics, computational biology, and mathematical demography to develop biomarkers of aging for humans and animal models using high-dimensional omics data. As PI or co-Investigator on multiple NIH-, Foundation-, and University-funded projects, Dr. Levine has extensive experience using systems-level and machine learning approaches to track epigenetic, transcriptomic, and proteomic changes with aging and incorporate this information to develop measures of risk stratification for major chronic diseases, such as cancer and Alzheimer’s disease. Her work also involves development of systems-level outcome measures of aging, aimed at facilitating evaluation for geroprotective interventions. A number of the existing biological aging measures she has developed are being applied in both basic and observational research. Dr. Levine is also Bioinformatics Advisor at Elysium Health, where she led the development of Index, an at-home test that measures an individual’s cumulative rate of aging, using the next-generation technology Algorithmic Platform for Epigenetic Examination (APEX). Prior to her time at Yale, Dr. Levine served as a postdoctoral fellow in human genetics at the UCLA David Geffen School of Medicine, where she worked with Steve Horvath, PhD, to help identify specific DNA methylation sites along the epigenome that are highly correlated with biomarkers of biological age and chronological age. Dr. Levine holds a BS and PhD from the University of Southern California. |